South Coast Pirates and Western Bulls kicked off their campaign with wins against USIU Martial and Kabarak Univesity in Championship matches played on Saturday.
Pirates landed three tries to beat USIU at KCB Sports Club. Joseph Musyoki, Nick Omodo and Steve Bosire scored Pirates tries in the win.
In Kakamega, Western Bulls ran five tries and converted two to pick maximum points from the match against Kabarak.
Andrew Odhiambo, Allan Kasitin Byrum Mukhoyi, Nickson Nyandieka and Willis Mwinamo scored Bulls five tries.
Newbies Shamas Foundation stunned former Kenya Cup side Kisumu 28-13 in a match played in Maseno. Eldoret RFC beat 2019/20 quarterfinalists Egerton 17-0.
Catholic Monks beat Mean Machine 27-20 while UoE beat Northern Suburbs 9-8.
Western Bulls 29-0 Kabarak University
Kisumu RFC 13-28 Shamas Foundation
Mean Machine 20-27 Catholic University
Northern Suburbs 8-9 UOE
Egerton University 0-17 Eldoret RFC
USIU 15-17 South Coast Pirates