Ben Youngs will make his 100th cap for England at scrum-half – becoming the second most capped England men’s player of all time after Jason Leonard (114 caps) as they tackle Italy on Saturday 31 October at Stadio Olimpico.
Youngs made his senior team debut against Scotland in March 2010, where he came on as a substitute in the Calcutta Cup.
Hooker Jamie George will also be making his 50th appearance and he will join Youngs in leading the side out on matchday.
Jonny Hill will make his England debut at lock, while Owen Farrell, starting at fly-half, will captain the side. Henry Slade is at the inside centre while Jonathan Joseph returns for England at outside centre.
George Furbank has been named at full-back with Jonny May and Anthony Watson on the wings. Kyle Sinckler will play tighthead and Mako Vunipola loosehead in the front row. Maro Itoje completes the tight five.
England need a bonus-point win to put them in contention for winning the tournament, depending on the result in France v Ireland, which follows the game in Rome.
— Guinness Six Nations (@SixNationsRugby) October 29, 2020
England squad: 15. George Furbank (Northampton Saints, 2 caps) 14. Anthony Watson (Bath Rugby, 43 caps) 13. Jonathan Joseph (Bath Rugby, 50 caps) 12. Henry Slade (Exeter Chiefs, 29 caps) 11. Jonny May (Gloucester Rugby, 56 caps) 10. Owen Farrell (Saracens, 83 caps) 9. Ben Youngs (Leicester Tigers, 99 caps) 1. Mako Vunipola (Saracens, 59 caps) 2. Jamie George (Saracens, 49 caps) 3. Kyle Sinckler (Bristol Bears, 35 caps) 4. Maro Itoje (Saracens, 38 caps) 5. Jonny Hill (Exeter Chiefs, uncapped) 6. Tom Curry (Sale Sharks, 23 caps) 7. Sam Underhill (Bath Rugby, 18 caps) 8. Billy Vunipola (Saracens, 51 caps)
REPLACEMENTS: 16. Tom Dunn, (Bath Rugby, uncapped) 17. Ellis Genge (Leicester Tigers, 18 caps) 18. Will Stuart (Bath Rugby, 3 caps) 19. Charlie Ewels (Bath Rugby, 15 caps) 20. Ben Earl (Bristol Bears, 3 caps) 21. Dan Robson (Wasps, 2 caps) 22. Ollie Lawrence (Worcester Warriors, uncapped) 23. Ollie Thorley (Gloucester Rugby, uncapped)