The 2019 Six Nations campaign finally kicks off on Friday evening in Paris with France hosting Wales.
Wales scrum-half Tomos Williams will make his Six Nations debut as other changes see prop Rob Evans and flanker Josh Navidi replace the injured Nicky Smith and Ellis Jenkins.
Ken Owens is set to become Wales’ most capped hooker as he earns his 61st appearance on Friday night and Adam Beard is picked to join Alun Wyn Jones in the second row as Rhys Patchell, Leigh Halfpenny, Scott Williams and Leon Brown all missed out through injury.
France have also named their team and have dropped a selection bombshell by dropping vice-captain Mathieu Bastareaud and selecting 19-year-old Romain Ntamack in the centre with Wesley Fofana, one of two debutants along with South Africa-born lock Paul Willemse.
France: 15-Maxime Medard, 14-Damian Penaud, 13-Wesley Fofana, 12-Romain Ntamack, 11-Yoann Huget, 10-Camille Lopez, 9-Morgan Parra; 1-Jefferson Poirot, 2-Guilhem Guirado (capt), 3-Uini Atonio, 4-Sebastien Vahaamahina, 5-Paul Willemse, 6-Wenceslas Lauret, 7-Arthur Iturria, 8-Louis Picamoles
Replacements: 16-Julien Marchand, 17-Dany Priso, 18-Demba Bamba, 19-Felix Lambey, 20-Gregory Alldritt, 21-Baptiste Serin, 22-Gael Fickou, 23-Geoffrey Doumayrou
Wales: 15-Liam Williams, 14-George North, 13-Jonathan Davies, 12-Hadleigh Parkes, 11-Josh Adams, 10-Gareth Anscombe, 9-Tomos Williams; 1-Rob Evans, 2-Ken Owens, 3-Tomas Francis, 4-Alun Wyn Jones (capt), 5-Adam Beard, 6-Josh Navidi, 7-Justin Tipuric, 8-Ross Moriarty
Replacements: 16-Elliot Dee, 17-Wyn Jones, 18-Samson Lee, 19-Cory Hill, 20-Aaron Wainwright, 21-Gareth Davies, 22-Dan Biggar, 23-Owen Watkin